5-Amino-1MQ
Coming soon5 Amino 1MQ5-Amino-1-methylquinolinium, a small molecule that is not a peptide. Researchers study methylquinolinium compounds as inhibitors of nicotinamide N-methyltransferase (NNMT) in cell culture and mouse models.
Supplied as a single-chamber lyophilized vial with a colour-coded cap (Mitochondrial and cofactors).
Research literature, not dosing or treatment instructions.
- Structure-activity work on small-molecule NNMT inhibitors identified N-methylquinolinium scaffolds with low micromolar inhibition, the scaffold class of 5-amino-1MQ. (PMID 28548833)
- Membrane-permeable methylquinolinium NNMT inhibitors were tested in cell culture and in mice on a high-fat diet. (PMID 29155147)
Add the solvent slowly along the vial wall; swirl gently, never shake. Allow to dissolve fully. Six-step guide with photos →
Concentration calculator only. Enter the mass being calculated; blend components are not added automatically. Products are for in-vitro research.
Keep the sealed vial at 2 to 8 °C, in its box and away from light. The label and the lot certificate carry the storage condition and expiry date of your lot.
Every lot of 5-Amino-1MQ gets its own certificate, published under the lot number printed on the vial label. Scan the QR code on the vial or enter its lot number to open the report.
- Purity (HPLC)Method and result for the lot
- Identity (LC-MS)Measured mass against the compound
- Lot numberThe same number as on the vial label
- LaboratoryNamed and signed in the report
Questions about 5-Amino-1MQ
How much published research is there on 5-Amino-1MQ?
The research library's PubMed search for 5-Amino-1MQ returned 34 records on 5 October 2026, 2 of them reviews. The library lists 5 studies chosen for what they measured. ClinicalTrials.gov lists no registered study naming 5-Amino-1MQ (checked 5 October 2026).
Is 5-Amino-1MQ an approved medicine?
No centrally authorised medicine containing 5-Amino-1MQ is listed in the EMA medicines database (checked 5 October 2026), and the research material we supply is not a medicine. It is supplied for in-vitro laboratory research only, not for human or veterinary use.
Which form of 5-Amino-1MQ is listed, the cation or the salt?
PubChem lists CAS 42464-96-0 as the iodide salt (C10H11IN2, 286.11 g/mol) of the 5-amino-1-methylquinolinium cation (C10H11N2+, 159.21 g/mol). The formula and weight on this page are those of the cation. The salt form of a supplied lot is read from its certificate.
How is the identity of 5-Amino-1MQ confirmed on a certificate?
A research-grade certificate of analysis typically reports identity by mass spectrometry and purity by HPLC. The mass result is read against the average molecular weight of 159.21 g/mol listed on this page. The research library's guide to reading a certificate explains each field.
What other names is 5-Amino-1MQ published under?
5-Amino-1MQ is also written 5 Amino 1MQ and 5-amino-1-methylquinolinium. The catalog lists it under the name 5-Amino-1MQ.
Is this product for human use?
No. Peptency products are supplied for in-vitro research only. Not for human or veterinary use, not for diagnosis or therapy.
What if my order arrives damaged or I cannot receive it?
We do not accept returns, because products are sealed research materials. If a parcel cannot be delivered, contact us and we help correct the address and trace the parcel. If an item arrives damaged, wrong or missing, contact us within 14 days with the order number and photos and we send a replacement or a one-time voucher for the affected items, our choice.
Where can I find shipping information?
Current shipping rates and delivery information are on the Shipping & payment page, and the rates that apply to your order are shown at checkout. 2 to 3 day delivery across central Europe, shipped in insulated packaging to keep vials cool in transit.
Often studied with
For research use only. Not for human or veterinary use.
What is 5-Amino-1MQ?
5-Amino-1MQ is 5-amino-1-methylquinolinium, a small molecule that is not a peptide. PubChem titles its record for CAS 42464-96-0 NNMTi, and the literature studies methylquinolinium compounds as inhibitors of nicotinamide N-methyltransferase (NNMT). We supply 5-Amino-1MQ as a lyophilized vial for in-vitro laboratory research only.
What are the chemical identifiers of 5-Amino-1MQ?
5-Amino-1MQ has the molecular formula C10H11N2+, an average molecular weight of 159.21 g/mol and CAS number 42464-96-0.
PubChem lists CAS 42464-96-0 as the iodide salt (C10H11IN2, 286.11 g/mol) of the 5-amino-1-methylquinolinium cation (C10H11N2+, 159.21 g/mol). The salt form of a supplied material is read from its certificate.
Chemistry checked against PubChem (CID 950107), 5 October 2026; full chemistry record in the research library.
What does published research on 5-Amino-1MQ cover?
A PubMed search for 5-Amino-1MQ returned 34 records on 5 October 2026, 2 of them reviews. Our research library lists 5 of these studies, chosen for what they measured.
- Structure-activity work on small-molecule NNMT inhibitors identified N-methylquinolinium scaffolds with low micromolar inhibition, the scaffold class of 5-amino-1MQ. (Neelakantan et al., J Med Chem, 2017; PMID 28548833)
- Membrane-permeable methylquinolinium NNMT inhibitors were tested in cell culture and in mice on a high-fat diet. (Neelakantan et al., Biochem Pharmacol, 2018; PMID 29155147)
Mechanism, every cited study and the regulator records are on the 5-Amino-1MQ page of the research library. Papers are listed by what they measured, not as evidence of any use.
How is 5-Amino-1MQ supplied and stored?
5-Amino-1MQ is supplied as a lyophilized (freeze-dried) powder in a sealed vial, for in-vitro laboratory research only. Our stated storage condition for the sealed lyophilized vial is 2 to 8 °C. The label and the lot certificate carry the lot-specific storage condition and expiry date.
What is the regulatory status of 5-Amino-1MQ?
The EMA medicines database (checked 5 October 2026) lists no centrally authorised medicine naming 5-Amino-1MQ as an active substance. National authorisations are not in that dataset.
No SmPC, PIL or PAR document in MHRA Products matches the exact name (checked 5 October 2026).
A regulator record is information about a database entry. It is not advice and not a statement that any use is lawful or unlawful in any country. How regulators approach research peptides.
Which related research pages and compounds are listed?
- 5-Amino-1MQ: chemistry, literature and regulatory status
- NAD+ metabolism and NNMT
- How to read a certificate of analysis
Related compounds in the catalog: